Eplerenone Final RGB
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چکیده
• Monographs for unlicensed drugs/indications must not be circulated to prescribers. • Not to be used for commercial purposes. • The information contained herein will be superseded in due course. • Copyright UKMIPG 2002. Date Published:December 2003 Monograph Number:3/03/05 Region of Origin to whom queries should be directed:West Midlands/National Prescribing Centre NEW DRUGS IN CLINICAL DEVELOPMENT
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متن کاملEffects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy study.
BACKGROUND Elevated renin-angiotensin-aldosterone system activity correlates with left ventricular hypertrophy (LVH) and cardiovascular risk, but the relative contributions of angiotensin II and aldosterone remain unclear. This study compared LVH regression during treatment with the selective aldosterone blocker eplerenone, enalapril, and their combination in patients with hypertension. METHO...
متن کاملEfficacy and tolerability of eplerenone and losartan in hypertensive black and white patients.
OBJECTIVES The purpose of this study was to evaluate the efficacy and tolerability of monotherapy with the selective aldosterone blocker eplerenone in both black and white patients with hypertension. BACKGROUND Essential hypertension and cardiovascular-renal-target organ damage is more prevalent in black than white adults in the U.S. METHODS Black (n = 348) and white (n = 203) patients with...
متن کاملEffects of the selective aldosterone blocker eplerenone versus the calcium antagonist amlodipine in systolic hypertension.
Eplerenone is a highly selective aldosterone blocker, which is under development for the treatment of hypertension and heart failure. To assess its usefulness in older patients with systolic hypertension and widened pulse pressure, we compared the effects of eplerenone with amlodipine, on clinic blood pressure (BP) and pulse pressure and in a subset of the patients, ambulatory BP, vascular comp...
متن کاملCost-effectiveness of eplerenone in treatment of cardio-vasculardiseases: a systematic review
Introduction: In recent years, a few studies have been conducted in the area of the cost-effectiveness of the Eplerenone; it's notable that coherent and clear evidence are not available. Therefore, this study aimed to systematically review studies of cost-effectiveness of Eplerenone in the treatment of cardio-vascular patients. Methods: This systematic review study was conducted in 2016. The...
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تاریخ انتشار 2004